| Date |
Speaker
streaming video |
room |
Title of the 1o Journal Paper |
Authors |
year
journal |
volume:
pages |
food |
| Aug 30 |
Cliff |
UCL
173 |
Why Story Telling in Science is Important
How to chose a paper, What makes a good talk, Guide to Seminar Design
Seminar Success Guide
Intinerary, Schedule and Organization
|
CH Summers |
2019 |
|
none |
| September 13 |
Kevin
Krupp |
UCL
173 |
Presynaptic serotonin 2A receptors modulate thalamocortical plasticity and associative learning
Background papers: Moreno et al., 2012 J Biol Chem 287:44301-44319 Identification of three residues essential for 5-hydroxytryptamine 2A-metabotropic glutamate 2 (5-HT2A-mGlu2) receptor heteromerization and its psychoactive behavioral function
Gewirtz, Chen, Terwilliger, Duman, Marek 2002 Pharm Biochem Behav 73:317-326 Modulation of DOI-induced increases in cortical BDNF expression by group II mGlu receptors |
A Barre
C Berthoux
D De Bundel
E Valjaent
J Bockaert
P Marin
C Becamel |
2016
PNAS |
10.1073/pnas/1525586113:
E1382-E1391 |
Jess |
| September 20 |
Jazmine
Yaeger |
UCL
173 |
Orexin depolarizes central amygdala neurons via orexin receptor 1, phospholipase C and sodium-calcium exchanger and modulates conditioned fear
Background papers: Liu, An, Li, Kuang, He, Guo, Ma, Zhang, Ji, Jiang 2015 biomaterials 80:133-45 Brain-targeted co-delivery of therapeutic gene and peptide by multifunctional nanoparticles in Alzheimer's disease mice
Harmon, Aly, Padegimas, Sesenoglu-Laird, Cooper, Wasczak 2014 Gene Therapy 21:514-521 Intranasal administration of plasmid DNA nanoparticles yields successful transfection and expression of a reporter protein in rat brain |
ET Dustrude
IF Caliman
CS Bernabe
SD Fitz
LA Grafe
S Bhatnagar
P Bonaventure
PL Johnson
AI Molosh
A Shekhar
|
2018
Frontiers in
Neuroscience |
12:
934: 1-13
10.3389/fnins.2018.00934 |
Eric S |
| September 27 |
Riley
Paulsen |
UCL
173 |
Single oral dose of cannabinoid derivate loaded PLGA nanocarriers relieves neuropathic pain for eleven days
Background papers:Martin-Banderas et al., 2015 Science Advances 1:e15002511-8 Cannabinoid derivate-loaded PLGA nanocarriers for oral administration: formulation, characterization, and cytotoxicity studies
Dziadulewicz et al., 2007 J Med Chem 50:3851-3856 Naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methanone: A potent, orally bioavailable human CB1/CB2 dual agonist with Antihyperalgesic Properties and restricted central nervous system penetration |
E Berrocoso
R Rey-Brea
M Fernández-Arévalo
JA Micó
L Martín-Banderas |
2017
Nanomedicine:
Nanotechnology,
Biology and
Medicine |
13:
2623–2632 |
Raegan |
| October 4 |
Eric
Graack |
UCL
173 |
An in vitro and in vivo study of peptide-functionalized nanoparticles for brain targeting: The importance of selective blood–brain barrier uptake
Background papers: Mohamed et al., 2018 NeuroImage: Clinical 19:716–726 Amyloid pathology fingerprint differentiates post-traumatic stress disorder and traumatic brain injury
Stegurová et al. 2014 J Immunological Methods 406:137-142 Gold nanoparticle-based immuno-PCR for detection of tau protein in cerebrospinal fluid |
GH Bode
G Coué
C Freese
KE Pickl
M Sanchez-Purrŕ
B Albaiges
S Borrós
EC van Winden
L-A Tziveleka
Z Sideratou
JFJ Engbersen
S Singh
K Albrecht
J Groll
M Möller
AJG Pötgens
C Schmitzk
E Fröhlich
C Grandfils
FM Sinner
J Kirkpatrick
HWM Steinbusch
H-G Frank
RE Unger
P Martinez-Martinez |
2017
Nanomedicine:
Nanotechnology,
Biology and
Medicine |
13:
1289-1300 |
Riley |
| October 11 |
Avery
Del
Grosso |
UCL
173 |
Near-infrared deep brain stimulation via upconversion nanoparticle–mediated optogenetics
Background papers: Wu et al., 2018 ACS Nano 10: 1060-1066 Dye-Sensitized Core/Active Shell Upconversion Nanoparticles for Optogenetics and Bioimaging Applications
Schmuckermair, Gaburro, Sah, Landgraf, Sartori, Singewald 2013 Neuropsychopharmacology 38: 1234-1244 Behavioral and Neurobiological Effects of Deep Brain Stimulation in a Mouse Model of High Anxiety- and Depression-Like Behavior
|
Shuo Chen
Adam Z. Weitemier
Xiao Zeng
Linmeng He
Xiyu Wang
Yanqiu Tao
Arthur J. Y. Huang
Yuki Hashimotodani
Masanobu Kano
Hirohide Iwasaki
Laxmi Kumar Parajuli
Shigeo Okabe
Daniel B. Loong Teh
Angelo H. All
Iku Tsutsui-Kimura
Kenji F. Tanaka
Xiaogang Liu
TJ McHugh |
2018
Science |
359:
679–684 |
Kevin |
| Oct 18, 25 |
|
|
Karger Workshop, JB Johnston Club for Evolutionary Neuroscience
Society for Neuroscience |
27th
48th |
Annual Meeting |
Washington
DC |
| November 1 |
Chad
Ryan |
UCL
173 |
Curcumin-loaded nanoparticles potently induce adult neurogenesis and reverse cognitive deficits in Alzheimer's Disease model via canonical Wnt/ß-Catenin pathway
Background papers:
McAvoy and Sahay, 2017 Neurotherapeutics 14: 630-645 Targeting adult neurogenesis to optimize hippocampal circuits in aging
Faghihi and Moustafa, 2016 J Integrative Neuroscience 15: 1-17 Impaired neurogenesis of the dentate gyrus is associated with pattern separation deficits: A computational study |
SK Tiwari
S Agarwal
B Seth
A Yadav
S Nair
P Bhatnagar
M Karmakar
M Kumari
LKS Chauhan
DK Patel
V Srivastava
D Singh
SK Gupta
A Tripathi
RK Chaturvedi
KC Gupta |
2014
ACSNano |
8:
76–103 |
Marie
Paul |
| November 8 |
Christa
Huber
Marie
Severson |
UCL
173 |
Surface functionalized exosomes as targeted drug delivery vehicles for cerebral ischemia therapy
Background papers:
Doeppner et al., 2015 Stem Cells Translational Medicine 4: 1131–1143 Extracellular vesicles improve post-stroke neuroregeneration and prevent postischemic immunosuppression
Samini et al., 2013 Stem Cells 24:1433–1440 Curcumin pretreatment attenuates brain lesion size and improves neurological function following traumatic brain injury in the rat
Nanotherapeutic approach for opiate addiction using DARPP-32 gene silencing in an animal model of opiate addiction
Background papers:
Bonoiu et al., 2009 PNAS 106: 5546–5550 Nanotechnology approach for drug addiction therapy: Gene silencing using delivery of gold nanorod-siRNA nanoplex in dopaminergic neurons
Zachariou et al., 2002 Biological Psychiatry 51:612–620 Reduction of cocaine place preference in mice lacking the protein phosphatase 1 inhibitors DARPP 32 or Inhibitor 1 |
T Tian
H-X Zhang
C-P He
S Fan
Y-L Zhu
C Qi
N-P Huang
Z-D Xiao
Z-H Lu
BA Tannous
J Gao
TA Ignatowski
R Aalinkeel
JL Reynolds
BB Nair
DE Sykes
CPK Gleason
WC Law
MJ Mammen
PN Prasad
SA Schwartz
SD Mahajanr |
2018
Biomaterials
2015
J Neuroimmune
Pharmacol |
150:
137-149
10:
136–152 |
Chad
Jaz |
| November 15 |
Eric
Sandhurst |
UCL
173 |
Stress-altered synaptic plasticity and damp signaling in the hippocampus-PFC axis; elucidating the significance of IGF-1/IGF-1R/CAMKIIa expression in neural changes associated with a prolonged exposure therapy
Background papers: Zhang et al., 2019 J Pharm Sci 108: 551-562 A novel approach via surface modification of degradable polymers with adhesive DOPA-IGF-1 for neural tissue engineering
Zhang, Hao, Yuan Zhang, Dong 2015 Annales Médico-Psychologiques 175: 889- 893 The significate of IGF-1 and IGF-1R in reducing PTSD cognitive function symptoms
|
OM Ogundele
PJ Ebenezer
CC Lee
J Francis |
2017
Neuroscience |
353:
147-165 |
Eric G |
| November 22 |
Jess
Hoynoski
Raegan
Nelson |
UCL
173 |
Locating the site of neuropathic pain in vivo using MMP-12-targeted magnetic nanoparticles
Background papers:
HF Miranda, F Sierralta, N Aranda, P Poblete, V Noriega, JC Prieto, 2018 Fundamental & Clinical Pharmacology 32: 581–588 Synergism between gabapentin–tramadol in experimental diabetic neuropathic pain
J Lalani,S Patil, A Kolate,R Lalani, A Misra 2015 AAPS PharmSciTech 16: Protein-functionalized PLGA nanoparticles of lamotrigine for neuropathic pain management
Brain-targeted intranasal delivery of dopamine with borneol and lactoferrin co-modified nanoparticles for treating Parkinson’s disease
Background papers:
Yan, Xu, Bi, Duan, Chu, Yu, Wu, Wang, Sun et al., 2018 International J Nanomedicine 13: 273–281 Lactoferrin-modified rotigotine nanoparticles for enhanced nose-to-brain delivery: LESA-MS/MS-based drug biodistribution, pharmacodynamics, and neuroprotective effects
Zhang, Han, Qin, Lu, Wang 2013 Pharm Res 30: 2560–2572 The use of borneol as an enhancer for targeting aprotinin-conjugated PEG-PLGA nanoparticles to the brain |
SF Husain
RWM Lam
T Hu
MWF Ng
ZQG Liau
K Nagata
S Khanna
Y Lam
K Bhakoo
RCM Ho
H-K Wong
S Tang
A Wang
X Yan
L Chu
X Yang
Y Song
K Sun
X Yu
R Liu
Z Wu
P Xue |
2018
Pain
Research and
Management
2019
Drug Delivery |
2019:
Article ID 9394715:
1–11
doi:10.1155/2019/9394715
19:
716–726 |
Christa |
| November |
28-29 |
|
Thanksgiving |
Pilgrims |
1622 |
1:
eat-
sleep |
| December 6 |
Paul Granaas |
UCL
173 |
Biodegradable nanoparticles containing mechanism based peptide
inhibitors reduce polyglutamine aggregation in cell models and alleviate motor symptoms in a Drosophila model of Huntington’s
Disease
Background papers:
Author 2019 ACS Applied Materials & Interfaces 11: 34725-34735 Selenium nanoparticles as an efficient nanomedicine for the therapy of Huntington’s Disease
BMDC Godinho, JR Ogier, R Darcy, CM O’Driscoll, JF Cryan 2013 Molecular Pharmaceutics 10: 640-649 Self-assembling modified ß-cyclodextrin nanoparticles as neuronal siRNA delivery vectors: Focus on Huntington’s Disease |
AS Joshi
V Singh
A Gahane
AK Thakur |
2019
ACS Chemical
Neuroscience |
10:
1603-1614 |
Avery |
|
|
|
Nanoparticles in Brain Therapy Take Home Messages |
|
|
|
|
Summers 